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Article

Oncocytic Thyroid Tumours With Pathogenic FLCN Mutations Mimic Oncocytic Papillary Thyroid Carcinoma on Fine-Needle Aspiration.

Cytopathology : official journal of the British Society for Clinical Cytology - 1 Jan 2026

Ashraf Adeel M, Hassan Faisal, Dawkins Adrian A, Dueber Julie C, Allison Derek B, Bocklage Thèrése J

Abstract excerpt

BACKGROUND: Thyroid tumours occur in patients with Birt-Hogg-Dubé syndrome (BHD), a condition caused by germline alterations in the FLCN gene that confers an increased cancer risk. Somatic FLCN mutations may also contribute to tumorigenesis. In this study, we present the first description of the cytopathology of two thyroid tumours evaluated by fine-needle aspiration (FNA) and harbouring pathogenic FLCN...

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Share to Adenoma, Oxyphilic
Share to Biopsy, Fine-Needle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Birt-Hogg-Dube Syndrome

Share to Diagnosis, Differential

Share to High-Throughput Nucleotide Sequencing

Share to Thyroid Cancer, Papillary

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Source

Identifiers

PMID: 40844232
DOI: 10.1111/cyt.70019

Genes

FLCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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