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A Five-Gene Stromal-EMT Signature Predicts Prognosis, Immunotherapy Resistance, and Therapeutic Vulnerability in Bladder Cancer

2026-08-20

Abstract excerpt

<h4>Background: </h4> Bladder cancer has entered an era in which immune checkpoint blockade (ICB) and antibody-drug conjugate (ADC)-based combinations are reshaping clinical management. However, transcriptomic scores that connect prognosis, tumor microenvironment state, and treatment response are incompletely defined. <h4>Methods:</h4> Open-access TCGA-BLCA RNA-seq, clinical, mutation, copy-number, and RPPA data w...

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Literature Corpus work
5208d169-731d-5738-a1fd-d8b399eb92f1
DOI
10.64898/2026.08.15.745016
Open publication

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A Five-Gene Stromal-EMT Signature Predicts Prognosis, Immunotherapy Resistance, and Therapeutic Vulnerability in Bladder CancerDOI 10.64898/2026.08.15.745016
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