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Article

rs.11196205 Variant in the TCF7L2 Gene is Associated with an Increased Cardiovascular Risk in Individuals with Hypertension and Diabetes.

Archives of medical research - 1 Jan 2026

Agostini Lívia da Cunha, Coelho Letícia Fernandes Dias, Machado E Silva Renata Bárbara, Silva Nayara Nascimento Toledo, Lopes Ana Cláudia Faria, Belo Vanessa de Almeida, Coura-Vital Wendel, Teixeira Luiz Fernando de Medeiros, Lima Angélica Alves, da Silva Glenda Nicioli

Abstract excerpt

BACKGROUND AND AIMS: The interaction between genetic polymorphisms and environmental factors increases the risk of developing a diabetic phenotype which is associated with systemic arterial hypertension (SAH) and cardiovascular diseases. Variants in the T-cell factor 7-like 2 (TCF7L2) gene have been associated with type 2 diabetes mellitus (T2DM). To investigate the association of the rs.11196205 polymorphism of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Transcription Factor 7-Like 2 Protein

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Identifiers

PMID: 40834719
DOI: 10.1016/j.arcmed.2025.103268

Genes

TCF7L2
AIP
TG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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