Article
TCF7L2 gene polymorphisms and type 2 diabetes: association with diabetic retinopathy and cardiovascular autonomic neuropathy.
Acta diabetologica - 1 Oct 2013
Ciccacci Cinzia, Di Fusco Davide, Cacciotti Laura, Morganti Roberto, D'Amato Cinzia, Novelli Giuseppe, Sangiuolo Federica, Spallone Vincenza, Borgiani Paola
Abstract excerpt
Type 2 diabetes (T2DM) is a complex disease resulting from the contribution of both environmental and genetic factors. Recently, the list of genes implicated in the susceptibility to T2DM has substantially grown, also as a consequence of the great development of the genome-wide association studies in the last decade. Common polymorphisms in TCF7L2 gene have shown to have a strong effect with respect to many other...
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