Article
Sex-specific associations of TCF7L2 variants with fasting glucose, type 2 diabetes and coronary heart disease among Turkish adults.
Anatolian journal of cardiology - 1 Nov 2020
Yüzbaşıoğulları Ayşe Berna, Kömürcü-Bayrak Evrim, Onat Altan, Can Gunay, Mononen Nina, Laaksonen Reijo, Kähönen Mika, Lehtimäki Terho, Erginel-Ünaltuna Nihan
Abstract excerpt
OBJECTIVE: TCF7L2 is a repressor and transactivator of genes, and its variants are strongly associated with diabetes. This study aimed to evaluate the sex-specific relationship between the most common TCF7L2 gene variants (-98368G>T, rs12255372 and -47833C>T, rs7903146) with diabetes and coronary heart disease in Turkish Adult Risk Factor (TARF) Study. METHODS: Single nucleotide variants (SNVs) have been...
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