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Outlier maternal haplogroups N5 and X2 and their potential role in elevated tuberculosis prevalence among the Sahariya tribe.

Mitochondrion - 1 Nov 2025

Das Debashruti, Singh Prajjval Pratap, Desai Shailesh, Mishra Rahul Kumar, Shrivastava Pankaj, Suravajhala Prashanth, Tamang Rakesh, Chaubey Gyaneshwer

Abstract excerpt

India bears the largest burden of tuberculosis (TB) cases in the world. Prior studies have highlighted significantly higher pulmonary TB among the Sahariya tribal population in Central India. The disease susceptibility of a population to disease may be influenced by genetic ancestry. In this context, we investigated the maternal genetic ancestry of the Sahariya in relation to their neighbouring tribal...

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PMID: 40829724
DOI: 10.1016/j.mito.2025.102078

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