npstat: An Efficient Tool to Explore the Population Genome Variability and Divergence Using Pool Sequencing Data.

Abstract excerpt

Pool sequencing has emerged as a valuable approach in ecological studies, particularly when dealing with very small organisms (with limited amount of DNA available), when distinguishing individual organisms is a challenge (e.g., in colonies, microbiome), when there is a trade-off between the sequencing cost and the number of individuals to sequence, when the main goal is to estimate nucleotide variability and...

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