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A multi-cohort validated OXPHOS signature predicts survival and immune profiles in grade II/III glioma patients

1 Aug 2025

Abstract excerpt

Introduction: Grade II/III gliomas are invasive brain tumors with a high risk of malignant progression and significant clinical heterogeneity, highlighting the urgent need for reliable prognostic biomarkers to guide personalized treatment strategies. This study aimed to investigate the molecular mechanisms driving glioma progression and to identify potential therapeutic targets. Methods: We analyzed 200...

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PMID: 40821817
DOI: 10.3389/fimmu.2025.1638824

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