Article
Investigation of delamanid, bedaquiline, and linezolid resistance rates and related gene mutations in multidrug-resistant Mycobacterium tuberculosis in regional tuberculosis reference laboratories of Iran.
BMC microbiology - 15 Aug 2025
Ahmad Khosravi Nazanin, Khosravi Azar Dokht, Hashemzadeh Mohammad, Savari Mohammad, Saki Morteza
Abstract excerpt
INTRODUCTION: So far, there are scarce data on resistance to delamanid (DLM), bedaquiline (BDQ), and linezolid (LZD) antibiotics and related gene mutations in multidrug-resistant Mycobacterium tuberculosis (MDR M. tuberculosis) from Iran. Hence, this study aimed to investigate the DLM, BDQ, and L...
Topics
- Mycobacterium tuberculosis
- Iran
- Nitroimidazoles
- Oxazoles
- Microbial Sensitivity Tests
- Humans
- Antitubercular Agents
- Tuberculosis, Multidrug-Resistant
- Diarylquinolines
- Drug Resistance, Multiple, Bacterial
- Cross-Sectional Studies
- Mutation
- Linezolid
- Sputum