Article
The telomere syndromes.
Nature reviews. Genetics - 1 Oct 2012
Armanios Mary, Blackburn Elizabeth H
Abstract excerpt
There has been mounting evidence of a causal role for telomere dysfunction in a number of degenerative disorders. Their manifestations encompass common disease states such as idiopathic pulmonary fibrosis and bone marrow failure. Although these disorders seem to be clinically diverse, collectively they comprise a single syndrome spectrum defined by the short telomere defect. Here we review the manifestations and...
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