Insect antiviral Mx-like protein forms biomolecular condensates to promote viral capsid ubiquitinated degradation

Abstract excerpt

Insects transmit diverse arthropod-borne viruses. However, it remains largely unknown whether insect innate immune pathways regulate the expression of antiviral factors to mediate the degradation of viral capsids. Here, we discover that transcription factor Dorsal in leafhopper Toll immune pathway binds to the promoter of vertebrate homolog myxovirus resistance-like (MxL) protein to activate its transcription....

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