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Article

Utilising Next-Generation Sequencing to Explore the Molecular Etiology of Short Root Anomaly.

Orthodontics & craniofacial research - 1 Dec 2025

Joy Emily A, Crossman David K, MacDougall Mary, Hassan Quamarul, Lamani Ejvis

Abstract excerpt

OBJECTIVE: Short Root Anomaly (SRA) is a genetic dental disorder affecting tooth root development. The affected teeth have abnormally short roots and significantly reduced root to crown ratios. The aim of this study was to determine the mode of inheritance and the molecular aetiology of SRA in identified Hispanic families. METHODS: Dental history was taken from 5 Hispanic families. SRA diagnosis was based on...

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PMID: 40781924
DOI: 10.1111/ocr.70015
PMCID: PMC12927132

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