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Network-based approach identifies key genes associated with tumor heterogeneity in HPV positive and negative head and neck cancer patients

7 Aug 2025

Abstract excerpt

Head and Neck Squamous Cell Carcinoma (HNSCC) is the seventh most prevalent cancer worldwide and is classified as human papillomavirus (HPV) positive or negative. Substantial heterogeneity has been observed in the two groups, posing a significant clinical challenge. In the disease context, global transcriptional changes are likely driven by a few key genes that reflect the disease etiology more accurately...

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PMID: 40775425
DOI: 10.1038/s41598-025-13604-0

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