Article
Longitudinal study reveals plasma glycans associations with prediabetes/type 2 diabetes in KORA study.
Cardiovascular diabetology - 6 Aug 2025
Niu Jiefei, Rodriguez Elke, Štambuk Tamara, Trbojević-Akmačić Irena, Mraz Nikol, Seissler Jochen, Skurk Thomas, Schlesinger Sabrina, Peters Annette, Lauc Gordan, Gieger Christian, Grallert Harald
Abstract excerpt
BACKGROUND: Altered plasma N-glycosylation is increasingly recognized as a contributor to metabolic dysregulation. This study aimed to investigate the role of plasma N-glycans in glucose metabolism and the progression from normoglycemia to prediabetes and type 2 diabetes (T2D). METHODS: We analyzed longitudinal data from 473 participants in the Cooperative Health Research in the Region of Augsburg (KORA) cohort...
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