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Article

Gain and Loss of Heterozygosity in the Genome of the Asexual Nematode Halicephalobus mephisto.

Journal of molecular evolution - 1 Aug 2025

Amini Ali, Bracht John R

Abstract excerpt

Asexual reproduction often leads to loss of genetic diversity, but several mechanisms have evolved to maintain heterozygosity. The subterrestrial nematode, Halicephalobus mephisto, reproduces parthenogenetically, and here, we investigate how its genetic diversity - 1.15% SNP heterozygosity-is retained from generation to generation. To test for loss of heterozygosity, we PCR-typed 56 individual animals at two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40770573
DOI: 10.1007/s00239-025-10259-3
PMCID: PMC12354626

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