Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human-Based Technologies in Cardiovascular Pharmacology Research.

Journal of cardiovascular pharmacology - 1 Nov 2025

Biondi-Zoccai Giuseppe, Frati Giacomo, Carnevale Roberto, Booz George W

Abstract excerpt

ABSTRACT: Human-based technologies are revolutionizing cardiovascular pharmacology by offering innovative platforms that more accurately reflect human biology and disease mechanisms than traditional animal models. These approaches include tissue chips, microphysiologic systems, engineered heart tissues, cardiac organoids, and human cardiac slices-each contributing to substantial improvements in drug testing,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiology
Share to Cardiovascular Agents
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Discovery

Share to Gene Editing

Share to Phenotype

Share to Precision Medicine

Share to Translational Research, Biomedical

Source

Identifiers

PMID: 40763280
DOI: 10.1097/FJC.0000000000001745

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human-Based Technologies in Cardiovascular Pharmacology Research.PMID 40763280Read ↗

Opportunities and challenges for the use of human samples in translational cardiovascular research: a scientific statement of the ESC Working Group on Cellular Biology of the Heart, the ESC Working Group on Cardiovascular Surgery, the ESC Council on Basic Cardiovascular Science, the ESC Scientists of Tomorrow, the European Association of Percutaneous Cardiovascular Interventions of the ESC, and the Heart Failure Association of the ESCSemantic proximity Read ↗

High throughput physiological screening of iPSC-derived cardiomyocytes for drug development.Semantic proximity Read ↗

Models of the Human Heart for Biomedical Research: Opportunities and ChallengesSemantic proximity Read ↗

Human-induced pluripotent stem cells as models for rare cardiovascular diseases: from evidence-based medicine to precision medicineSemantic proximity Read ↗

Cardiovascular Precision Medicine in the Genomics EraSemantic proximity Read ↗

Harnessing human genetics and stem cells for precision cardiovascular medicineSemantic proximity Read ↗

The American Heart Association's New Institute for Precision Cardiovascular Medicine.Semantic proximity Read ↗

Novel stem cell-based drug discovery platforms for cardiovascular disease.Semantic proximity Read ↗

Reversal of contractile defects by mediating calcium homeostasis in human mini-heart models of heart failure with preserved ejection fraction (HFpEF) leads to first-in-human gene therapy clinical trialSemantic proximity Read ↗

Organs-on-chip models for cardiovascular drug development.Semantic proximity Read ↗

From novel discovery tools and biomarkers to precision medicine—basic cardiovascular science highlights of 2021/22Semantic proximity Read ↗

Induced pluripotent stem cells for cardiovascular disease: from product-focused disease modeling to process-focused disease discovery.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.