Article
Plasmid-deficient Chlamydia muridarum fail to induce immune pathology and protect against oviduct disease.
Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2007
O'Connell Catherine M, Ingalls Robin R, Andrews Charles W, Scurlock Amy M, Darville Toni
Abstract excerpt
Chlamydia trachomatis is the most prevalent sexually transmitted bacterial infection in the world. In women, genital infection can cause endometritis and pelvic inflammatory disease with the severe sequelae of ectopic pregnancy or infertility. Chlamydia sp. do not damage tissues directly, but induce an injurious host inflammatory response at the infected site. In the murine model of genital disease with Chlamydia...
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