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The Cancer Genome in the Long Reads Era.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2025

Ermini Luca

Abstract excerpt

Cancer genomics, driven by advancements in sequencing technologies, is rapidly transforming our understanding of tumor biology. The advent of high-throughput short-read sequencing technologies has enabled a paradigm shift in cancer genomics, providing unprecedented resolution of mutations that drive tumorigenesis. Initially, short-read sequencing dominated the field, revealing the repertoire of mutational...

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PMID: 40736904
DOI: 10.1007/978-1-0716-4702-8_15

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