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Identification of differentially expressed genes associated with ferroptosis in ulcerative colitis

29 Jul 2025

Abstract excerpt

PURPOSE: To identify ferroptosis-related genes associated with the development of Ulcerative colitis (UC), through bioinformatics and basic experiments. METHODS: Ferroptosis-related genes were identified from UC microarray data extracted from the GEO database and FerrDb. GO and KEGG pathway enrichment analyses were performed. Hub genes were identified through PPI analysis, leading to TF-hub gene and miRNA-hub...

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Cancer-related molecular mechanisms research
Ferroptosis and cancer prognosis
Immune cells in cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40729322
DOI: 10.1371/journal.pone.0327990

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