Article

Identification of hub genes and key pathways in pediatric Crohn’s disease using next generation sequencing and bioinformatics analysis

2022-07-28

Abstract excerpt

Pediatric Crohn Disease (CD) also known as inflammatory bowel diseases, affects millions of people all over the world. The aim of this investigation is to identify the key genes in CD and uncover their potential functions. We downloaded the next generation sequencing (NGS) dataset GSE101794 from the Gene Expression Omnibus (GEO) database. The NGS dataset GSE101794 was used to screen differentially expressed genes...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c6ee740b-6f52-5d1e-abe5-fea9940369de
DOI: 10.1101/2022.07.27.501664

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of hub genes and key pathways in pediatric Crohn’s disease using next generation sequencing and bioinformatics analysisDOI 10.1101/2022.07.27.501664Read

Identification of differentially expressed genes and enriched pathways in inflammatory bowel disease using bioinformatics and next generation sequencing data analysisSemantic proximity Read

Identifying hub genes and miRNAs in Crohn’s disease by bioinformatics analysisSemantic proximity Read

Integrative Bioinformatics Analysis of Single Cell RNA-Sequencing Data Reveals Key Regulatory Genes and Therapeutic Targets in Inflammatory Bowel DiseaseSemantic proximity Read

Identification and validation of the common pathogenesis and hub biomarkers in Hirschsprung disease complicated with Crohn’s diseaseSemantic proximity Read

Uncovering potential novel biomarkers in Crohn's disease using integrated bioinformatics analysisSemantic proximity Read

Exploring the potential common genetic characteristics and molecular mechanisms between inflammatory bowel disease and atherosclerosis using bioinformatics analysis and machine learningSemantic proximity Read

Identification of differentially expressed genes, associated functional terms pathways, and candidate diagnostic biomarkers in inflammatory bowel diseases by bioinformatics analysisSemantic proximity Read

Comprehensive Identification of Potential Biomarkers Using Next Generation Sequencing Based Bioinformatics and Exploration of Therapeutic Molecules by Molecular Docking Studies for Inflammatory Bowel Disease.Semantic proximity Read

Identification and Analysis of Key Genes Associated with Ulcerative Colitis by Integrated Bioinformatics MethodsSemantic proximity Read

MicroRNA expression analysis for identification of biomarkers in inflammatory bowel disease subtypesSemantic proximity Read

GBP4 is an Accurate Diagnostic Biomarker and a Potential Treatment Target for Crohn’s DiseaseSemantic proximity Read

Identification of shared genes of atherosclerosis and Crohn's disease based on bioinformatics and machine learning algorithmSemantic proximity Read