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Comprehensive genomic profiling of over 10,000 advanced solid tumors.

Oncotarget - 25 Jul 2025

De La O Jean-Paul, Hoag Jess R, Deem Angela K, Wang Min, Starodynov Arthur, Udhane Sameer S, LoBello Janine R, Therala Nishitha, Hall David W, Basu Gargi D, Baehner Frederick L

Abstract excerpt

PURPOSE: To summarize clinically relevant genomic alterations in solid tumor samples from over 10,000 patients. METHODS: Descriptive statistics were used to summarize findings of retrospectively analyzed OncoExTra assay data from solid tumor samples. RESULTS: The analysis cohort included 11,091 solid tumor samples from 10,768 patients. Therapeutically actionable alterations were present in 92.0% of patient...

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PMID: 40711866
DOI: 10.18632/oncotarget.28757
PMCID: PMC12406462

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