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Article

Deoxyelephantopin induces cell death in oral cancer cells via the downregulation of AKT1-mTOR-mediated mechanisms

1 Apr 2025

Abstract excerpt

Background: ), has shown promising anti-cancer activity. Aim: By focussing on the AKT1/mTOR signalling pathway, which controls tumour cell proliferation and survival, this study explores the molecular underpinnings behind DET's therapeutic potential in OSCC. Materials and Methods: cytotoxicity of DET on human oral cancer cells (KB) was evaluated using the 3 (4,5 dimethylthiazol 2 yl) 2,5 diphenyltetrazolium...

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Share to Cancer, Stress, Anesthesia, and Immune Response
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PMID: 40703820
DOI: 10.4103/jomfp.jomfp_41_25

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