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Investigating genetic links between blood metabolites and preeclampsia.

BMC women's health - 5 Apr 2024

Lin Qiannan, Li Siyu, Wang Huiyan, Zhou Wenbo

Abstract excerpt

BACKGROUND: Observational studies have revealed that metabolic disorders are closely related to the development of preeclampsia (PE). However, there is still a research gap on the causal role of metabolites in promoting or preventing PE. We aimed to systematically explore the causal association between circulating metabolites and PE. METHODS: Single nucleotide polymorphisms (SNPs) from genome-wide association...

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Citrulline
Genetic Predisposition to Disease
Genome-Wide Association Study
Lactic Acid
Pre-Eclampsia

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PMID: 38580943
DOI: 10.1186/s12905-024-03000-7
PMCID: PMC10996307

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