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Article

C-C chemokine ligand 5 from women subcutaneous adipose tissue has a central role in vascular aging.

Cardiovascular diabetology - 18 Jul 2025

Le Pelletier Laura, Ngono Ayissi Kenza, Gorwood Jennifer, Capel Emilie, Morichon Romain, Mantecon Matthieu, Auclair Martine, Alili Rohia, Katlama Christine, Cuzin Lise, Atlan Michael, Beaupère Carine, Poitou Christine, Boccara Franck, Fève Bruno, Capeau Jacqueline, Lagathu Claire, Béréziat Véronique

Abstract excerpt

BACKGROUND: Aging is associated with adipose tissue alterations, oxidative stress, and fibrosis and the onset of cardiometabolic complications. While it has been shown that perivascular adipose tissue (PVAT) contributes to vascular damage, the involvement of subcutaneous adipose tissue (SCAT) - particularly through its secretory activity - in vascular aging remains poorly understood. Previously, we have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40682056
DOI: 10.1186/s12933-025-02815-4
PMCID: PMC12275387

Genes

CCL5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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