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Restricting intracellular Salmonella proliferation by coordinating p-TBK1 mediated mitophagy and xenophagy

15 Jul 2025

Abstract excerpt

Mitophagy is essential for eliminating dysfunctional mitochondria and is closely implicated in the immune evasion of several pathogens, including S. typhimurium. However, the specific mechanisms regarding the interaction between S. typhimurium and host cells in relation to mitophagy and xenophagy and their contribution to pathogen survival are unclear. Herein, using both in vitro and in vivo systems, we found...

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PMID: 40660474
DOI: 10.1080/15548627.2025.2534298

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