Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival

Abstract excerpt

Mitophagy is a selective autophagy mechanism for eliminating damaged mitochondria and plays a crucial role in the immune evasion of some viruses and bacteria. Here, we report that Mycobacterium bovis (M. bovis) utilizes host mitophagy to suppress host xenophagy to enhance its intracellular survival. M. bovis is the causative agent of animal tuberculosis and human tuberculosis. In the current study, we show that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autophagy in Disease and Therapy
• Share to Heme Oxygenase-1 and Carbon Monoxide
• Share to Sirtuins and Resveratrol in Medicine