Machine learning-based preoperative prediction of IDH mutation status in adult gliomas using clinical features.

Abstract excerpt

BACKGROUND: As isocitrate dehydrogenase (IDH) mutation status represents a critical prognostic factor in adult gliomas, there is a demand for a straightforward but effective predictive model to facilitate rapid preoperative diagnosis. METHODS: A cohort of 418 adult glioma patients from our institution were retrospectively enrolled and randomly partitioned into training (70%) and internal validation (30%) sets....

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