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The role of ubiquitination in microbial infection induced endothelial dysfunction: potential therapeutic targets for sepsis

2 Sept 2023

Abstract excerpt

INTRODUCTION: The ubiquitin system is an evolutionarily conserved and universal means of protein modification that regulates many essential cellular processes. Endothelial dysfunction plays a critical role in the pathophysiology of sepsis and organ failure. However, the mechanisms underlying the ubiquitination-mediated regulation on endothelial dysfunction are not fully understood. AREAS COVERED: Here we review...

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PMID: 37688775
DOI: 10.1080/14728222.2023.2257888

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