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Ultra-sensitive detection of microRNA in intraocular fluid using optical fiber sensing technology for central nervous system lymphoma diagnosis

1 Jul 2025

Abstract excerpt

MicroRNA (miRNA) in aqueous humor holds significant promise as a non-invasive biomarker of primary central nervous system lymphoma (PCNSL), enabling early diagnosis and prognosis. However, current methods for miRNA detection often suffer from limitations affecting sensitivity, specificity, and clinical applicability. This study introduces a novel black phosphorus (BP)-enhanced fiber-optic surface plasmon...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40639395
DOI: 10.1088/1361-6633/adee44

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