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Comparative and clinical impact of targeted next-generation sequencing in pediatric pneumonia diagnosis and treatment

25 Jun 2025

Abstract excerpt

Background Community-acquired pneumonia (CAP) remains a significant cause of pediatric morbidity and mortality worldwide. Conventional microbial tests (CMTs) frequently fail to accurately identify pathogens, especially in cases involving co-infections or less common organisms. Targeted next-generation sequencing (tNGS) presents a promising alternative, offering comprehensive pathogen detection. Methods A...

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PMID: 40636506
DOI: 10.3389/fmicb.2025.1590792

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