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Microbiological diagnostic performance of metagenomic next-generation sequencing compared with conventional culture for patients with community-acquired pneumonia

16 Mar 2023

Abstract excerpt

Background Community-acquired pneumonia (CAP) is an extraordinarily heterogeneous illness, both in the range of responsible pathogens and the host response. Metagenomic next-generation sequencing (mNGS) is a promising technology for pathogen detection. However, the clinical application of mNGS for pathogen detection remains challenging. Methods A total of 205 patients with CAP admitted to the intensive care unit...

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PMID: 37009509
DOI: 10.3389/fcimb.2023.1136588

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