Hydroxytyrosol induced ferroptosis through Nrf2 signaling pathway in colorectal cancer cells

Abstract excerpt

In recent years, the incidence of colorectal cancer is still on the rise. The killing of tumor cells through chemotherapy and/or radiation therapy is the mainstay of clinical anticolorectal cancer therapy, but is limited by drug and radiation resistance of tumor cells. Ferroptosis, a novel mode of programmed cell death, plays an important role in antitumor therapy. Ferroptosis inducers have been extensively...

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