Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Introducing a framework for within-host dynamics and mutations modelling of H5N1 influenza infection in humans.

Journal of the Royal Society, Interface - 1 Jul 2025

Higgins Daniel, Looker Joshua, Sunnucks Robert, Carruthers Jonathan, Finnie Thomas, Keeling Matt J, Hill Edward M

Abstract excerpt

Avian influenza A(H5N1) poses a public health risk due to its pandemic potential should the virus mutate to become human-to-human transmissible. To date, reported influenza A(H5N1) human cases have typically occurred in the lower respiratory tract with a high case fatality rate. There is prior evidence of some influenza A(H5N1) strains being a small number of amino acid mutations away from achieving droplet...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Influenza A Virus, H5N1 Subtype
Share to Influenza, Human

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Biological

Share to Mutation

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 40592463
DOI: 10.1098/rsif.2024.0910
PMCID: PMC12212982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Introducing a framework for within-host dynamics and mutations modelling of H5N1 influenza infection in humans.PMID 40592463Read ↗

Introducing a framework for within-host dynamics and mutations modelling of H5N1 influenza infection in humansSemantic proximity Read ↗

The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host.Semantic proximity Read ↗

Modelling the outbreak of infectious disease following mutation from a non-transmissible strain.Semantic proximity Read ↗

Looking beyond the H5 avian influenza viruses.Semantic proximity Read ↗

An agent-based nested model integrating within-host and between-host mechanisms to predict an epidemicSemantic proximity Read ↗

Quantifying the risk of pandemic influenza virus evolution by mutation and re-assortment.Semantic proximity Read ↗

Effects of Transmission Bottlenecks on the Diversity of Influenza A Virus.Semantic proximity Read ↗

Transmission cycles generate diversity in pathogenic virusesSemantic proximity Read ↗

Avian influenza viruses that cause highly virulent infections in humans exhibit distinct replicative properties in contrast to human H1N1 virusesSemantic proximity Read ↗

Minimal transmission in an influenza A (H3N2) human challenge-transmission model within a controlled exposure environmentSemantic proximity Read ↗

Multiscale Model Within-host and Between-host for Viral Infectious DiseasesSemantic proximity Read ↗

Quantifying the relationship between within-host dynamics and transmission for viral diseases of livestockSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.