Article
Pathogenesis of polycystic ovary syndrome: multifactorial assessment from the foetal stage to menopause.
Reproduction (Cambridge, England) - 1 Jul 2015
de Melo Anderson Sanches, Dias Sabrine Vilan, Cavalli Ricardo de Carvalho, Cardoso Viviane Cunha, Bettiol Heloisa, Barbieri Marco Antonio, Ferriani Rui Alberto, Vieira Carolina Sales
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a multifactorial disorder that arises from interactions between genetic, environmental and intra-uterine factors. Small-for-gestational-age (SGA) babies and the daughters of mothers with PCOS represent possible postnatal clinical targets for developmental programming by steroid excess. The presence of excess glucocorticoids and/or androgens during foetal organogenesis and...
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