Article
Side-by-Side Comparison of Culture Media Uncovers Phenotypic and Functional Differences in Primary Mouse Aortic Mural Cells.
Cells - 19 Jun 2025
Ghasemi Iman, Gogiraju Rajinikanth, Khraisat Sana'a, Pagel Sven, Graf Claudine, Brandt Moritz, Madhusudhan Thati, Wenzel Philip, Luxán Guillermo, Lurz Philipp, Bochenek Magdalena L, Schäfer Katrin
Abstract excerpt
(1) Background: Vascular mural cells reside in the media and outer layers of the vessel wall. Their ability to proliferate and migrate or to change phenotype in response to external cues is a central feature of the vascular response to injury. Genetically engineered mice are used for loss- or gain-of-function analyses or lineage tracing in vivo, their primary cells for mechanistic studies in vitro. Whether and...
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