From genomics to treatment: overcoming pan-drug-resistant Klebsiella pneumoniae in clinical settings

Abstract excerpt

Introduction: The spread pan-drug resistant pathogens pose a critical challenge to current therapies, resulting in high mortality and necessitating alternative approaches. Methods: We report pan-drug resistant Klebsiella pneumoniae isolates from five patients in a single hospital, including resistance to cefiderocol and cefepime-zidebactam in one isolate. Results: Whole-genome sequencing identified blaNDM-5 and...

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