Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stepwise evolution of pandrug-resistance in Klebsiella pneumoniae.

Scientific reports - 19 Oct 2015

Zowawi Hosam M, Forde Brian M, Alfaresi Mubarak, Alzarouni Abdulqadir, Farahat Yasser, Chong Teik-Min, Yin Wai-Fong, Chan Kok-Gan, Li Jian, Schembri Mark A, Beatson Scott A, Paterson David L

Abstract excerpt

Carbapenem resistant Enterobacteriaceae (CRE) pose an urgent risk to global human health. CRE that are non-susceptible to all commercially available antibiotics threaten to return us to the pre-antibiotic era. Using Single Molecule Real Time (SMRT) sequencing we determined the complete genome of a pandrug-resistant Klebsiella pneumoniae isolate, representing the first complete genome sequence of CRE resistant to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbapenems
Share to Chromosomes, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Transposable Elements

Share to Gene Dosage

Share to Gene Order

Share to Genome, Bacterial

Share to Klebsiella pneumoniae

Share to Mutagenesis, Insertional

Source

Open in PubMed Open full text

Identifiers

PMID: 26478520
DOI: 10.1038/srep15082
PMCID: PMC4609946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stepwise evolution of pandrug-resistance in Klebsiella pneumoniae.PMID 26478520Read ↗

Stepwise evolution of carbapenem-resistance, captured in patient samples and evident in global genomics of <i>Klebsiella pneumoniae</i>Semantic proximity Read ↗

Genomic characterization of a pandrug-resistant <i>Klebsiella pneumoniae</i> belonging to the high-risk ST11 in the Brazilian Amazon regionSemantic proximity Read ↗

The mecillinam resistome in Klebsiella pneumoniae: how resistance to a one-target β-lactam triggers a diversity of responses.Semantic proximity Read ↗

In vivo Emergence of Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae Mediated by Premature Termination of the mgrB Gene RegulatorSemantic proximity Read ↗

Whole genome analysis reveals chromosomal and plasmid-mediated convergence of drug resistance in Klebsiella pneumoniae isolates.Semantic proximity Read ↗

A phylogenomic approach for the analysis of colistin resistance-associated genes in Klebsiella pneumoniae, its mutational diversity and implications for phenotypic resistance.Semantic proximity Read ↗

Genomically Informed Surveillance for Carbapenem-Resistant Enterobacteriaceae in a Health Care System.Semantic proximity Read ↗

An Overview on Phenotypic and Genotypic Characterisation of Carbapenem-Resistant Enterobacterales.Semantic proximity Read ↗

Molecular Mechanisms of Colistin Resistance in Klebsiella pneumoniae in a Tertiary Care Teaching HospitalSemantic proximity Read ↗

<i>Klebsiella pneumoniae</i> as a key trafficker of drug resistance genes from environmental to clinically important bacteriaSemantic proximity Read ↗

ESBL-Producing Escherichia coli and Klebsiella pneumoniae Exhibit Divergent Paths During In-Human Evolution Towards Carbapenem ResistanceSemantic proximity Read ↗

Identification of a novel mutation involved in colistin resistance in Klebsiella pneumoniae through Next-Generation Sequencing (NGS) based approaches.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.