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Article

Preliminary Insights Into the Relationship Between the Gut Microbiome and Host Genome in Posttraumatic Stress Disorder.

Genes, brain, and behavior - 1 Jun 2025

O'Hare Michaela A, Rust Carlien, Malan-Müller Stefanie, Pirovano Walter, Lowry Christopher A, Ramaboli Matsepo, van den Heuvel Leigh L, Seedat Soraya, Hemmings Sian M J

Abstract excerpt

Posttraumatic stress disorder (PTSD) may develop following trauma exposure; however, not all trauma-exposed individuals develop PTSD, suggesting the presence of susceptibility and resilience factors. The gut microbiome and host genome, which are interconnected, have been implicated in the aetiology of PTSD. However, their interaction has yet to be investigated in a South African population. Using genome-wide...

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Identifiers

PMID: 40492293
DOI: 10.1111/gbb.70025
PMCID: PMC12149761

Genes

PGC
PROM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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