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Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

9 Jun 2025

Abstract excerpt

In recent years, a growing number of studies have disclosed the substantial role of macrophages-key immune cells-in the pathological process of intervertebral disc degeneration. Researchers have categorised macrophage phenotypes into M1 and M2 polarisation, associating these polarisations with intervertebral disc degeneration. Essentially, macrophage phenotypes can be classified as either pro-inflammatory or...

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PMID: 40488295
DOI: 10.1111/cpr.70068

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