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Article

Identification of genetic biomarkers of blood cholesterol levels using whole gene pathogenicity modelling.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2025

Sunny Sharon, Cheng Guo, Haria Joshua, Nazari Iman, Chauhan Jagmohan, Ennis Sarah

Abstract excerpt

Elevated cholesterol increases risk of diseases such as heart disease, chronic kidney disease and diabetes and early detection and diagnosis is desirable to enable preventative intervention. This study seeks to elucidate genetic factors affecting low-density lipoprotein cholesterol (LDL-C) levels in blood, enabling development of personalised strategies for lipid management and cardiovascular disease prevention....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 40473938
DOI: 10.1007/s00335-025-10140-0
PMCID: PMC12408753

Genes

PCSK9
APOE
BPIFB6
CLU
FAIM
LDLR
SAA1
SLAMF9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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