Article
Crosstalk Between the Oncoproteins of High-Risk Human Papillomaviruses Types 16 and 18 in Colorectal Cancer Cell Models.
Cancer reports (Hoboken, N.J.) - 1 Jun 2025
Fernandes Queenie, Inchakalody Varghese Philipose, Mestiri Sarra, Bedhiafi Takwa, Hydrose Shereena, Bashraheel Sara S, Merhi Maysaloun, Dermime Said, Al Moustafa Ala-Eddin
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) represents a major fraction of the total cancer burden worldwide. It has been recently identified that various high-risk Human Papillomaviruses (HPVs) are present in human CRCs, where they play a critical role in the development and progression of the cancer. AIMS: In this study, we explored the synergistic effect of the E6/E7 viral oncoproteins of the two most frequently...
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