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Article

Epigenetic age acceleration mediates the association between low-grade systemic inflammation and cardiovascular diseases: insight from the NHANES 1999–2002

31 May 2025

Abstract excerpt

BACKGROUND: Currently, with the global aging of the population, inflammation, recognized as a hallmark in age-related diseases, has been studied and linked to cardiovascular diseases (CVD). However, limited evidence on whether inflammation modifies epigenetic aging and affects CVD risk. METHODS: This study included 404 CVD patients and 1941 non-CVD individuals from the 1999-2002 National Health and Nutrition...

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PMID: 40450302
DOI: 10.1186/s13148-025-01895-z

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