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Defective autophagic flux aggravates cadmium-induced Sertoli cell apoptosis

16 Feb 2024

Abstract excerpt

The male reproductive dysfunction accounts for 50% of infertile couples in the world. Cadmium (Cd) is one of the most harmful heavy metals to both the environment and inhabitants. Accumulating data suggest that Cd could cause male infertility. Sertoli cell (SC) is a somatic cell of testis and a key regulator of spermatogenesis by providing physical and nutritional support for developing sperm. Many studies showed...

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PMID: 38367604
DOI: 10.1016/j.ecoenv.2024.116095

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