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Article

Deciphering the Role of Ferroptosis in the Pathogenesis of Peripheral Artery Disease Myopathy

12 May 2025

Abstract excerpt

This study investigates ferroptosis in the context of peripheral artery disease (PAD), a vascular disease characterized by atherosclerosis of the lower extremities. Muscle atrophy and increased oxidative stress are hallmarks of PAD and correlate with worse clinical outcomes. Given ferroptosis’ association with oxidative stress, we explored its role in PAD myopathy by examining gene and protein markers related to...

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PMID: 40427725
DOI: 10.3390/biology14050537

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