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Genetic Variation in the blaZ Gene Leading to the BORSA Phenotype in Staphylococcus aureus

29 Apr 2025

Abstract excerpt

Background/Objectives: Staphylococcus aureus is a leading cause of bacteraemia in Danish hospitals. Approximately 70% of clinical S. aureus isolates are penicillin-resistant, which is predominantly due to blaZ-mediated β-lactamase production. Methods: A collection of 489 S. aureus strains derived from bacteraemia were cultured and their genomes sequenced. Results: From this collection, 71% of isolates were...

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PMID: 40426516
DOI: 10.3390/antibiotics14050449

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