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A class A β-lactamase produced by borderline oxacillin-resistant Staphylococcus aureus hydrolyses oxacillin

19 Mar 2020

Abstract excerpt

OBJECTIVES: Recently, mecA-negative Staphylococcus aureus strains with decreased susceptibility to oxacillin have been sporadically reported worldwide. They have been called borderline oxacillin-resistant S. aureus (BORSA). S. aureus β-lactamase (BlaZ), which is encoded by the blaZ gene, is categorized as a class A β-lactamase (penicillinase); hence, its hydrolytic activity against oxacillin, cephems, and...

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PMID: 32200127
DOI: 10.1016/j.jgar.2020.03.002

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