Enhanced SNP genotyping with symmetric multinomial logistic regression.

Abstract excerpt

In genotyping, determining single nucleotide polymorphisms (SNPs) is standard practice, but it becomes difficult when analysing small quantities of input DNA, as is often required in forensic applications. Existing SNP genotyping methods, such as the HID SNP Genotyper Plugin (HSG) from Thermo Fisher Scientific, perform well with adequate DNA input levels but often produce erroneously called genotypes when DNA...

Topics

• Polymorphism, Single Nucleotide
• Humans
• Logistic Models
• Genotyping Techniques
• Genotype
• DNA