Article
More than meets the eye: mutation of the white gene in Drosophila has broad phenotypic and transcriptomic effects.
Genetics - 9 Jul 2025
Rickle April, Sudhakar Krittika, Booms Alix, Stirtz Ellen, Lempradl Adelheid
Abstract excerpt
The white gene, one of the most widely used genetic markers in Drosophila research, serves as a standard background mutation for transgene insertions and genetic manipulations. While its primary function involves eye pigmentation, mutations in white have been associated with diverse phenotypic effects, including those related to metabolism, behavior, and stress responses. However, many of the published studies do...
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