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Article

Ligand-receptor interaction atlas within and between tumor cells and T cells in lung adenocarcinoma

1 Jan 2020

Abstract excerpt

Purpose: Lung adenocarcinoma (LUAD) is the leading cause of cancer-related deaths worldwide. Although tumor cell-T cell interactions are known to play a fundamental role in promoting tumor progression, these interactions have not been explored in LUAD. Methods: The 10x genomics single-cell RNA sequencing (scRNA-seq) and gene expression data of LUAD patients were obtained from ArrayExpress, TCGA, and GEO...

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PMID: 32549766
DOI: 10.7150/ijbs.42080

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