Article
Digital twins, synthetic patient data, and in-silico trials: can they empower paediatric clinical trials?
1 May 2025
Abstract excerpt
Randomised controlled trials are the gold standard to assess the effectiveness and safety of clinical interventions; however, many paediatric trials are discontinued early due to challenges in patient enrolment. Hence, most paediatric clinical trials suffer from lack of adequate power. Additionally, trials are expensive and might expose patients to unproven therapies. Alternatives to overcome these issues using...
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